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目的分析大黄虫丸加味辅助化疗治疗非霍奇金淋巴瘤的临床近期疗效及药物不良反应,为临床非霍奇金淋巴瘤治疗方案选择提供参考。方法选取2011年1月至2015年12月我院收治的80例非霍奇金淋巴瘤患者作为研究对象,分为每组40例的对照组和观察组,对照组采用化疗治疗,观察组患者在化疗治疗期间再予以大黄虫丸加味治疗,两组患者均治疗2个疗程,比较两组患者治疗期间药物不良反应及临床疗效。结果对照组患者治疗过程中,药物不良反应34例,不良反应发生率85.0%,观察组患者不良反应33例,不良反应发生率82.5%,两组患者药物发不良反应率比较,差异无统计学意义。对照组患者临床总有效率57.5%,观察组患者临床总有效率85.0%,观察组临床总有效率明显高于对照组,组间比较差异有统计学意义(P<0.05)。结论大黄虫丸加味辅助化疗治疗非霍奇金淋巴瘤,可有效提升患者的临床疗效,具有较高的临床价值,可进一步对其治疗方案进行优化研究,从而提高非霍奇金淋巴瘤的治疗效果。
Objective To analyze the clinical efficacy and adverse drug reactions of rhubarb worm pills plus adjuvant chemotherapy in the treatment of non-Hodgkin’s lymphoma and to provide a reference for the selection of clinical non-Hodgkin’s lymphoma. Methods From January 2011 to December 2015 in our hospital treated 80 cases of non-Hodgkin’s lymphoma patients were divided into 40 cases in each control group and observation group, the control group with chemotherapy, the observation group patients During the chemotherapy treatment, rhubarb worm pills were additionally given to the patients. Two groups of patients were treated with two courses of treatment. The adverse drug reaction and clinical efficacy were compared between the two groups. Results In the control group, 34 cases were adverse drug reactions, the incidence of adverse reactions was 85.0%, 33 cases were adverse reactions in the observation group, the incidence of adverse reactions was 82.5%. There was no significant difference in adverse drug reaction between the two groups significance. The total clinical effective rate was 57.5% in the control group and 85.0% in the observation group. The total effective rate in the observation group was significantly higher than that in the control group, with significant difference between the two groups (P <0.05). Conclusion Rhubarb worm pills plus adjuvant chemotherapy in the treatment of non-Hodgkin’s lymphoma, which can effectively improve the clinical efficacy of patients with high clinical value, further optimization of their treatment options to improve the treatment of non-Hodgkin’s lymphoma effect.