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生长激素(GH)对人体的生长发育起着重要的调控作用。有实验数据显示GH/IGF-1轴可能促进肿瘤的发生发展。重组人生长激素(rhGH)究竟能否应用于恶性肿瘤病人?阻断GH-IGF轴对恶性肿瘤病人是否有积极的治疗作用?现就GH相关肿瘤生物学效应的研究进展作一综述。
Growth hormone (GH) plays an important role in regulating the growth and development of the human body. Some experimental data show that GH / IGF-1 axis may promote tumor development. Whether recombinant human growth hormone (rhGH) can be applied to patients with malignant tumors? Blocking the GH-IGF axis for patients with malignant tumors have a positive therapeutic effect? Now on the GH-related biological effects of tumor progression are reviewed.