经蝶窦入路切除垂体瘤首先由Schloffer于1907年介绍,因手术困难和有严重并发症,未被广泛采用。60年代Guiot和Hardy对该入路进行改进后,经口、鼻中隔、蝶窦入路切除垂体瘤的显微手术已普遍推广。我院自1982年2月至1984年6月经该入路手术75例,其中垂体腺瘤切除66例,效果满意。现就手术技巧方面(以垂体腺瘤切除为主)的体会交流如下、 Transsphenoidal resection of the pituitary tumor first introduced by Schloffer in 1907, due to surgical difficulties and serious complications, has not been widely used. After the improvement of the approach by Guiot and Hardy in the 1960s, microsurgical resection of pituitary tumors by oral, nasal septum, sphenoid sinus approach has been widely promoted. Our hospital from February 1982 to June 1984 through the operation of 75 cases, of which 66 cases of pituitary adenoma resection, the effect is satisfactory. Now on the surgical techniques (mainly to pituitary adenomas) exchange of experience is as follows,