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肢端肥大症是一种由垂体腺瘤分泌的生长激素(GH)过多所引起的疾病。治疗的目的在于抑制GH的分泌及肿瘤对正常垂体及周围组织的压迫。近年来,随着病理、药理及显微外科技术等方面的发展,肢端肥大症的治疗取得了突破性进展。本文旨在对肢端肥大症的治疗近况作一介绍。 一、手术疗法 (一)冷冻及显微手术治疗肢端肥大症:手术治疗是肢端肥大症的主要治疗方法。治疗效果无可争议。当前手术治疗包括经鼻窦冷冻摘除术及经蝶窦显微手术两类。
Acromegaly is a disease caused by excess growth hormone (GH) secreted by pituitary adenomas. The purpose of the treatment is to inhibit the secretion of GH and the compression of the tumor on the normal pituitary and surrounding tissues. In recent years, with the development of pathology, pharmacology, and microsurgical techniques, a breakthrough in the treatment of acromegaly has been achieved. This article aims to provide an introduction to the treatment of acromegaly. First, surgery (a) frozen and microsurgery treatment of acromegaly: surgical treatment of acromegaly is the main treatment. The therapeutic effect is undisputed. The current surgical treatment includes frozen sinus excision and transsphenoidal microsurgery.