EB病毒(EBV)是DNA肿瘤病毒,是人类单核细胞增多症(IM)的病原因子。血清学和流行病学资料表明EBV与鼻咽癌(NPC)和伯基特氏淋巴瘤(BL)有密切关系。EBV能在某些灵长类动物中诱发恶性肿瘤,在人鼻咽癌(NPC)和淋巴瘤(BL)的癌瘤细胞中有明确的EBV标志(EBV DNA和EBNA)。因此EBV的致瘤作用受到了广泛的重视。Henle曾指出, Epstein-Barr virus (EBV) is a DNA tumor virus that is the etiological agent of human mononucleosis (IM). Serological and epidemiological data indicate that EBV is closely related to nasopharyngeal carcinoma (NPC) and Burkitt’s lymphoma (BL). EBV can induce malignant tumors in certain primates and has clear EBV markers (EBV DNA and EBNA) in human nasopharyngeal carcinoma (NPC) and lymphoma (BL) cancer cells. Therefore, the oncogenic effect of EBV has received extensive attention. Henle once pointed out that