精神兴奋药物成瘾是指反复使用具有成瘾性的药物,造成中枢神经系统发生适应性变化而导致躯体耐受及心理依赖复杂的病理生理过程,并伴有觅药、用药等强迫行为。由于成瘾形成涉及多种复杂神经机制、转录机制、信号传导机制等,因此 Psychoactive drug addiction refers to the repeated use of addictive drugs, resulting in adaptive changes in the central nervous system leading to physical tolerance and psychological dependence on complex pathophysiological processes, accompanied by looking for drugs, medication and other compulsions. As addiction involves a variety of complex neural mechanisms, transcriptional mechanisms, signaling mechanisms, etc.