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A 4-year-old boy was hospitalized with fever for 2 days. He had no history of taking aspirin previously. Physical examination revealed a temperature of 40.2℃, pharynx congestion,enlarged tonsils and normal lungs.Lab findings included WBC count of 13.5x109/L with 84% neutrophils and 16% lymphocytes.The patient was diagnosed as acute tonsillitis and treated with DL-lysine aspirin 0.3g by intramuscular injection.10 minutes later,the boy developed nausea,non-projectile vomiting and dull look. It was considered the warning signs of convulsions induced by hyperpyrexia,and treated with phenobarbital 0.1g by intramuscular injection.He had shortness of breath,moist rales with bilateral lungs and 80% serum oxygen saturation.The symptoms were not lessened after giving oxygen supplement and hydrocotisone etc.2 hours later,the boy developed dyspnea,cyanosis and paleness. His conditions were deteriorated progressively after treatment including trachea intubation and mechanical ventilation.He died of respiratory and circulatory failure.
A 4-year-old boy was hospitalized with fever for 2 days. He had no history of taking aspirin previously. Physical examination revealed a temperature of 40.2 ° C, pharynx congestion, enlarged tonsils and normal lungs. Inspection results included WBC count of 13.5x109 / L with 84% neutrophils and 16% lymphocytes. The patient was diagnosed as acute tonsillitis and treated with DL-lysine aspirin 0.3g by intramuscular injection.10 minutes later, the boy developed nausea, non-projectile vomiting and dull look. It was considered the warning signs of convulsions induced by hyperpyrexia, and treated with phenobarbital 0.1g by intramuscular injection. He had shortness of breath, moist rales with bilateral lungs and 80% serum oxygen saturation.The symptoms were not lessened after giving oxygen supplement and hydrocotisone etc .2 hours later, the boy developed dyspnea, cyanosis and paleness. His conditions were deteriorated progressively after treatment including trachea intubation and mechanical ventilation .He died of respiratory and circulatory failure.