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异名 AH 19065,Zantac 化学名 N-[2-[[5-[(二甲基氨基)甲基]呋喃-2-基甲基]硫基]乙基]-N’-甲基-2-硝基-1,1-乙烯基二胺盐酸盐药效分类抗溃疡药开发单位 (英)Glaxo 上市厂商 (英)Claxo 1981年11月首次报道 Jap Soc Gastroenterol,Proc 22:226(22-24 Oct 1980)。药理本品为选择性的组胺H_2受体竞争性拮抗剂,为甲氰咪胍的类似物。它对基础的胃酸分泌以及刺激后的胃酸分泌具有抑制作用,能减少分泌物的量以及酸和胃蛋白酶的含量。体内抑制胃分泌的作用比甲氰咪
Synonyms AH 19065, Zantac Chemical name N- [2 - [[5 - [(dimethylamino) methyl] furan-2- ylmethyl] thio] ethyl] -N’-methyl-2- Nitro-1,1-vinyldiamine hydrochloride Pharmacodynamic Category Antiulcer Drug Development Unit Glaxo Listed Company Claxo First reported in November 1981 Jap Soc Gastroenterol, Proc 22: 226 (22-24 Oct 1980). Pharmacology This product is a selective antagonist of histamine H 2 receptor, an analog of cimetidine. It has an inhibitory effect on basal gastric acid secretion and stimulated gastric acid secretion, reducing the amount of secretions and the content of acid and pepsin. In vivo inhibition of gastric secretion than the role of cyanide microphone