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观察香菇多糖配合化疗治疗对恶性血液病患者细胞免疫功能的影响。恶性血液病６８例（ＡＬ３０例，ＣＬ９例，ＭＬ２９例）分为两组，香菇多糖治疗组４４例，单纯化疗组２４例，香菇多糖组治疗后ＣＤ４、ＣＤ４／ＣＤ８及ＮＫ细胞活性明显提高，ＣＤ８及ＨＬＡＤＲ抗原活性减低（Ｐ＜０．０５），治疗有效率及Ｈｂ、ＷＢＣ亦高于单纯化疗组（Ｐ＜０．０５）。结果提示，香菇多糖配合化疗可提高恶性血液病细胞免疫功能及机体抗肿瘤活性，并改善临床症状及提高化疗疗效
Observe the effect of lentinan combined with chemotherapy on cellular immune function in patients with hematological malignancies. Sixty-eight malignant hematological diseases (AL30, CL9, and ML29) were divided into two groups: lentinan treatment group (44 cases) and chemotherapy group (24 cases). After lentinan treatment, the activity of CD4, CD4/CD8, and NK cells increased significantly. The activity of CD8 and HLA-DR antigens was reduced (P<0.05). The treatment efficiency and Hb and WBC were also higher than those of chemotherapy alone (P<0.05). The results suggest that lentinan combined with chemotherapy can improve the cellular immune function and antitumor activity of hematological malignancies, and improve the clinical symptoms and efficacy of chemotherapy.