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β_2微球蛋白(β_2-microglobulin简称β_2MG)是体内细胞合成的一种低分子量蛋白质,因电泳显于β_2区带而得名,是人体组织相容性抗原的一个亚单位。1968年由Berggard等人从肾小管性疾病患者尿中分离出来。1971年Evrin等用放射免疫分析法测定β_2MG以来,此项检测临床应用的报道较多,但用来监测肾移植病人排异反应的报告尚少。本文对慢性肾炎尿毒症进行同种异体肾移植术的患者,动态检测患者血、尿标本中β_2MG的变化,作为肾移植术后排异反应的一项客观指标,结果满意,现报告如下。检测对象与方法一、检测对象:本院收治的99例慢性肾炎尿毒症
β_2 microglobulin (β_2-microglobulin referred to as β_2MG) is a low molecular weight protein synthesized by cells in vivo. It is named after β_2 band by electrophoresis and is a subunit of human histocompatibility antigen. 1968 by Berggard et al urine from patients with renal tubular disease isolated. Evrin and other radioimmunoassay in 1971, since the determination of β_2MG, the detection of clinical application of this report more, but used to monitor renal transplant rejection response to patients is still low. In this paper, patients with chronic nephritis uremic allograft renal transplantation, dynamic detection of blood and urine samples in patients with β 2 MG changes, as rejection after renal transplantation an objective indicator of the results are satisfactory, are as follows. Test objects and methods First, the test object: 99 cases admitted to our hospital chronic nephritis uremia