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本文应用ABC免疫组化法对37例HSK病人40眼及14例非HSK病例14眼角膜上皮细胞涂片进行HSV-1抗原检测,结果敏感性97.5%、特异性100%。作者认为该方法不仅可用于临床HSK病人早期、快速诊断,而且还是监测HSK复发及观察应用抗病毒药物疗效的有实用价值的诊断方法。
In this study, HSV-1 antigen was detected by ABC immunohistochemistry in 40 eyes of 37 patients with HSK and 14 eyes of 14 patients with non-HSK. The sensitivity and specificity were 97.5% and 100%, respectively. The authors think this method not only can be used for early and rapid diagnosis of clinical HSK patients, but also is a useful diagnostic method for monitoring the recurrence of HSK and observing the effect of antiviral drugs.