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甲巯丙脯酸(Captopril,CPT)是一种口服的血管紧张素转化酶抑制剂,已广泛应用于临床,不仅用于顽固性高血压、肾性高血压、难治性心力衰竭,而且用于治疗类风湿性关节炎、银屑病、肝硬化腹水、嗜铬细胞瘤等疾病。随着其广泛应用,副作用也明显表现出来,有的可能危及生命。我院1987年1月至1988年12月,有1979例病人应用 CPT 治疗,发生不良反应者184例(9.3%),现分析报道如下。一、一般资料 184例中,男108例,占58.7%;年龄21～78岁,平均46.3岁。女76例,占41.3%;年龄23～81岁,平均38.4岁。顽固性高血压46例,肾性高血压18例,难治性心力衰竭51例,妊娠高血压综合征11例,类风湿性关节炎18例,偏头痛13例,巴
Captopril (CPT), an oral angiotensin-converting enzyme inhibitor, has been widely used clinically, not only for refractory hypertension, renal hypertension, refractory heart failure, In the treatment of rheumatoid arthritis, psoriasis, cirrhosis, pheochromocytoma and other diseases. With its widespread use, side effects are also evident, and some may endanger life. Our hospital from January 1987 to December 1988, there are 1979 cases of patients treated with CPT, 184 cases of adverse reactions (9.3%), the analysis is reported as follows. First, the general information 184 cases, 108 males, accounting for 58.7%; aged 21 to 78 years, mean 46.3 years. 76 females, accounting for 41.3%; aged 23 to 81 years old, with an average of 38.4 years old. 46 cases of refractory hypertension, renal hypertension in 18 cases, 51 cases of refractory heart failure, pregnancy induced hypertension syndrome in 11 cases, 18 cases of rheumatoid arthritis, migraine in 13 cases, Pakistan