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作者应用图像分析技术，观察了６０Ｃｏγ射线在两种剂量率条件下体外诱发人胚肺细胞转化的细胞和细胞核形态计量学参数的变化特点，分析了各形态计量学参数与剂量率及照射剂量两个因素间的定量关系。结果说明：人胚肺细胞的面积、等效直径和形状因子及细胞核的面积、周长、等效直径和核浆比等，均随着照射剂量的增加而增大，用线性平方模型（Ｅ＝ａ＋ｂＤ＋ｃＤ２）描述这种剂量效应关系为最好；上述细胞和细胞核各参数与剂量率和照射剂量间经数学分析处理，除细胞等效直径仅与照射剂量相关外，其余参数均与上述两因素有密切的函数依赖关系，高剂量组的损伤效应明显高于低剂量率组。
The author applied the image analysis technology to observe the characteristics of 60Coγ-ray changes in morphological parameters of cells and nuclei induced by human embryonic lung cells induced by 60Coγ-rays in vitro under two dose rates. The morphometric parameters and dose rates and dose The quantitative relationship between factors. The results showed that the area, the equivalent diameter and the shape factor of human embryonic lung cells and the area, perimeter, equivalent diameter and nucleus to plasma ratio of nucleus increased with the increase of irradiation dose. The linear square model (E = A + bD + cD2) described the best dose-response relationship; the above parameters of the cells and nuclei and the dose rate and irradiation dose by mathematical analysis, except for the equivalent cell diameter and radiation dose-related, the remaining parameters are the above two factors There is a close functional dependency, and the damage effect of high dose group is obviously higher than that of low dose rate group.