在单因素基础上,采用响应面分析法对影响蜂胶黄酮提取率的主要因素(提取时间、提取温度、提取固液比和乙醇浓度)进行优化,建立影响因素与响应值(黄酮提取率)之间的函数关系。根据回归方程寻优得出,基于实际条件取工艺条件为温度22℃、料液比17mL/g、提取时间30h、乙醇浓度74%。黄酮的提取率的理论值为32.53%。 On the basis of single factor, response surface analysis was used to optimize the main factors affecting the extraction rate of propolis flavonoids (extraction time, extraction temperature, extraction of solid-liquid ratio and ethanol concentration), and to establish the influencing factors and response value (flavonoid extraction rate) The functional relationship between. According to the regression equation, the optimum conditions were as follows: the temperature was 22 ℃, the solid-liquid ratio was 17mL / g, the extraction time was 30h and the concentration of ethanol was 74% based on the actual conditions. The theoretical value of the extraction rate of flavonoids is 32.53%.