十多年来,GPC法获得广泛应用和迅速发展,它的基本理论工作就显得跟不上。即使在基本的分离机理方面,至今还处于百家争鸣之中,尚无定论。为了简单起见,人们假定不存在溶质和担体(胶)之间的相互作用。作为一般观察到的现象,溶质按其尺寸大小的差别而被分离。但为什么如此,就有种种理论解释,兹粗略介绍如下: For more than a decade, GPC has gained wide application and rapid development, and its basic theoretical work can not keep up. Even in the basic mechanism of separation, there are still hundreds of schools of thought, so far as inconclusive. For the sake of simplicity, one assumes that there is no interaction between solute and support (glue). As a generally observed phenomenon, solutes are separated by their size differences. But why, there are a variety of theoretical explanations, it is roughly described as follows: