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用体外造血祖细胞培养技术证明Ⅱ型登革病毒对红系造血祖细胞(CFUE)也有生长抑制作用,CFU-E的抑制效应与病毒的浓度呈正相关。说明登革热病人虽然无贫血表现,但骨髓红系造血已受到病毒的影响。
Using in vitro hematopoietic progenitor cell culture technology, it was demonstrated that dengue virus type Ⅱ also inhibited the growth of erythrocytic hematopoietic progenitor cells (CFUE). The inhibitory effect of CFU-E was positively correlated with the concentration of virus. Although dengue fever patients showed no anemia, but hematopoietic erythroid has been affected by the virus.