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胍类化合物是一种有机强碱 ,在生理条件下处于完全质子化状态 ,在催化有机酸碱反应时 ,催化性能明显优于无机碱和其它有机碱催化剂。此外 ,经修饰后的胍类化合物可以用于不对称催化 ;如果对其进行生理模拟 ,又可以用于酶催化反应。本文主要对胍类化合物所催化的反应进行介绍
Guanidine compounds is an organic strong base, under the physiological conditions in a fully protonated state, the catalytic performance of organic acid-base reaction, the catalytic performance was significantly better than the inorganic base and other organic base catalyst. In addition, the modified guanidine compounds can be used for asymmetric catalysis; if they are physiologically mimicked, they can be used for enzymatic catalysis. This article mainly introduces the reaction catalyzed by guanidine compounds