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我国有几个省的药品标准规定鱼腥草注射液的生产,多以生药1:1或1:2投料,用水蒸气蒸馏作其计算含量的标准。但是,干草与鲜草、嫩草与老草,含精油量大有不同。所以,生产出来的鱼腥草注射液,含精油量也各有不同,有的相差很大且没有检验标准。作者认为有必要改革生产工艺,统一标准,以保证药品质量安全有效。我们用72型分光光度计测试了10个批号鱼腥草注射液(定南制药厂生产)的吸收度,发现各有不同,有的相差很大。现将测定方法、结果以及对生产工艺的改革讨论于下。
There are several provinces in our country drug standards for the production of Houttuynia injection, and more crude drugs 1: 1 or 1: 2 feed, with steam distillation for the calculation of the content of the standard. However, hay and fresh grass, tender grass and old grass, with different amounts of essential oils. Therefore, the production of Houttuynia injection, including the amount of essential oils are also different, some very different and no test standards. The author believes it is necessary to reform the production process and standard to ensure the quality of medicines is safe and effective. We tested the absorbance of 10 lotus Houttuynia injection (manufactured by Dingnan Pharmaceutical Factory) using a 72 spectrophotometer and found that there were differences between them and some were quite different. The measurement methods, results and the reform of the production process are discussed below.