目的对胎儿患有染色体疾病进行诊断,争取优生,达到提高人口素质。方法超声引导下经腹穿刺进羊膜腔内抽羊水20ml,进行胎儿细胞染色体核型分析。结果在对258例胎儿羊水细胞染色体核型分析中,检测出异常核型15例,占5.82%。结论该方法进行产前诊断安全可靠,易被孕妇接受,值得推广。 Objective To diagnose fetus with chromosomal diseases and strive for eugenics to improve the quality of the population. Methods Ultrasound guided abdominal puncture into the amniotic cavity pumping amniotic fluid 20ml, fetal cell chromosome karyotype analysis. Results Of 258 cases of fetal amniotic fluid cell chromosome karyotype analysis, abnormal karyotype detected in 15 cases, accounting for 5.82%. Conclusion This method is safe and reliable for prenatal diagnosis and is easily accepted by pregnant women and is worth promoting.