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1988年4~5月对新疆巴楚县和农三师部分地区和团场中新疆出血热疫源地继续进行监测。以农三师50团为基地,东起夏河西至阿克沙克马拉勒(农三师48团),长约110km,北靠乌-喀公路,南抵叶尔羌河,宽约40km范围内共调查了17个点,主要以未开垦的荒漠牧场景观为主。监测内容包括对可疑病人、牧工和兽医以及部分健康人群的血清抗体检查、病原分离和治疗血清使用疗效观察;对48,50和53团不同连队共10个羊群血清抗体水平的调查和对部分绵羊血液进行病毒的分离;荒漠胡杨林中游离成蜱的病毒分离等项目。结果在4月底至5月下旬在50团发现3例新疆出血热病人,均经病毒分离确诊,其中2例因误诊耽误了抢救的机会而死亡;另外在查访53团和巴楚县医院时各发现1例病人,经血清学确诊。391份羊血清用ELISA抑制法检测抗体的阳性率为13.8%~77.4%;McAb-RPHI阳性率为13.8%~70.9%。从3例病人、羊血10份和9批亚洲璃眼蜱(每批50只)中分离到9株新疆出血热病毒。并用McAb致敏血球RPHA法检测血液中病毒抗原,达到了早期快速地确诊病人。通过1988年现场监测工作,进一步证实了1984年调查结果,巴楚地区的新疆出血热的疫源地活动性仍很强。人群和家畜抗体水平及亚洲璃眼蜱的带毒率20多年来基本没有变化,今年在这一局部地区发现5例病人,死亡2例,表明本病对当地人民健康和生命的威协仍然是一个现实问题。
From April to May 1988, he continued to monitor the Xinjiang Haemorrhagic Fever epidemic in some areas and groups in Bachu County and Nongsan Division in Xinjiang. Take the 50th division of the Nongsan division as the base, starting from Xiahexi to Akshakmalalou (48th division of Nongsanshi division) in the east, about 110km long. On the north of the Wu-Kala Highway, it goes to the Yarkand River in the south, with a total width of 40km A total of 17 points were surveyed, mainly based on uncultivated desert ranch landscapes. Surveillance includes the detection of serological antibodies to pathogenic bacteria, quarantine agents and some healthy people in suspicious patients, herdsmen and veterinarians, as well as the observation of therapeutic effects on serums. The investigation of serum antibody levels in 10 flocks of 48, 50 and 53 regiments, Sheep blood for virus isolation; desert Populus euphratica isolated ticks virus isolation and other projects. Results From the end of April to the end of May, three cases of hemorrhagic fever in Xinjiang were found in the 50th Corps. All of them were confirmed by virus isolation. Two of them died of misdiagnosis and delayed the rescue. In addition, One patient was found, confirmed by serology. The positive rate of 391 sheep serums detected by ELISA was 13.8% -77.4%. The positive rate of McAb-RPHI was 13.8% -70.9%. Nine strains of Xinjiang hemorrhagic fever virus were isolated from three patients, 10 sheep blood and 9 batches of Asian white-eye ticks (50 batches each). And with McAb sensitized blood cells RPHA method to detect the blood of viral antigens, reaching early rapid diagnosis of patients. Through the field monitoring in 1988, it further confirmed the findings of the 1984 survey that there was still a strong epidemic of endemic Xinjiang hemorrhagic fever in Bachu. Antibody levels in humans and fowl and the incidence of tick-borne Asian ophthalmia have remained virtually unchanged for more than two decades. Five patients were found in this part of the country this year, with two deaths indicating that the prevalence of this disease on the health and lives of local people is still A realistic problem.