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目的探讨甲基苯胺与氯胺酮滥用所致精神障碍患者临床精神症状对比。方法选取71例甲基苯胺滥用所致精神障碍患者为甲基苯胺组,另选70例氯胺酮滥用所致精神障碍患者为氯胺酮组,对两组患者临床精神症状进行对比分析。结果甲基苯胺组简明精神症状量表(BPRS)评分明显高于氯胺酮组,差异有统计学意义(P<0.05);甲基苯胺组思维障碍、敌对性、激活性等因子分明显高于氯胺酮组,差异有统计学意义(P<0.05),氯胺酮组缺乏活力、焦虑抑郁等因子分明显高于甲基苯胺组,差异有统计学意义(P<0.05);两组尿检阳性患者BPRS总分与因子分均高于尿检阴性组,差异有统计学意义(P<0.05)。结论甲基苯胺与氯胺酮滥用所致精神症状差异明显,临床需要根据其临床特征选择相应的治疗方案。
Objective To investigate the clinical psychiatric symptoms in patients with mental disorders caused by methylaniline and ketamine abuse. Methods A total of 71 patients with psychotic disorders caused by methylaniline abuse were selected as methylaniline group and 70 patients with psychotic disorders caused by abuse of ketamine were selected as ketamine group. Clinical psychiatric symptoms were compared between the two groups. Results The BPRS scores in methylaniline group were significantly higher than those in ketamine group (P <0.05). The scores of thinking disorder, hostility and activity in methylaniline group were significantly higher than those in ketamine group Group, the difference was statistically significant (P <0.05), ketamine group lack of vitality, anxiety and depression and other factors were significantly higher than the methylaniline group, the difference was statistically significant (P <0.05); two groups of urine test positive patients BPRS score And factor scores were higher than urine negative group, the difference was statistically significant (P <0.05). Conclusion The psychiatric symptoms caused by the abuse of methylaniline and ketamine are obviously different. The clinical need to choose the appropriate treatment according to their clinical characteristics.