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The activity of fumaric reductase in Cysticercus cellulosae tissue homogenate with albendazole and oxfendazole individually was detected. Results showed that the two kinds of drugs both could inhabite the activity of fumaric reductase. The results indicate that the mechanism of action of benzimidazole carbamate drugs is probably inhabiting the complex of fumaric reductase noncompetently, thus lead to the exhaostion of energy and death.
The activity of fumaric reductase in Cysticercus cellulosae tissue homogenate with albendazole and oxfendazole individually was detected. The results said that the two kinds of drugs both could inhabite the activity of fumaric reductase. The results that that the mechanism of action of benzimidazole carbamate drugs is probably inhabited the complex of fumaric reductase noncompetently, thus lead to the exhaostion of energy and death.