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应用ELISA法检测156例反复中上腹或脐周痛儿童血清抗-幽门螺杆菌IgG(抗-HPIgG),检出率56.4%(88/156);再对88例抗-HPIgG阳性者进行13C尿素呼气试验(13C-UBT),检出率50.1%(52/88),以明确诊断儿童幽门螺杆菌(HP)活动性感染。认为血清学方法可作为初步筛选试验,根据其结果再进行13C-UBT判断HP感染状态。二种试验方法结合具无例、准确、快速、相对经济的优点,可用于不愿接受内镜检查而又必须作出HP活动性感染诊断、进行根除治疗的上消化道疾病患儿。
Serum anti-Helicobacter pylori IgG (anti-Helicobacter pylori IgG) was detected in 156 children with repeated middle-upper or middle-umbilical pain by ELISA. The positive rate was 56.4% (88/156). Another 88 anti-HPIgG positive The 13C urea breath test (13C-UBT) was performed with a detection rate of 50.1% (52/88) in order to confirm the diagnosis of active H. pylori infection in children. Serological methods that can be used as a preliminary screening test, according to the results of further determination of 13C-UBT HP infection status. The two test methods combined with no case, accurate, fast, relatively economical advantages, can be used for unwilling to accept endoscopy but must make HP active infection diagnosis, eradication treatment of children with upper gastrointestinal diseases.