作者通过1例肾上腺皮质机能减退症病人在用利福平治疗后皮质素代谢改变的临床观察和对4例活动性肺结核病人的研究,发现利福平有一种未被认识的作用——增加皮质素分解的作用。并提示,可能是用利福平后肝微粒体酶诱导而致皮质素代谢的增加。病人23岁,男,患肾上腺皮质机能减退症伴肺尖结核浸润。立位血压80/50毫米汞柱,抗结核治疗前基础血浆皮质素6毫克/100毫升,血钠130毫当量/ The authors of one case of adrenocortical hypofunction patients treated with rifampin after corticosteroid metabolism in clinical observation and 4 cases of active pulmonary tuberculosis patients found that rifampin has an unrecognized role - increased cortical The role of prime decomposition. And suggested that may be the use of rifampicin liver microsomal enzyme induced increase in cortical metabolism. 23-year-old patient, male, suffering from adrenal hypofunction with pulmonary tuberculosis infiltration. Standing blood pressure 80/50 mm Hg, baseline plasma cortisol 6 mg / 100 ml before antituberculosis treatment, serum sodium 130 meq /