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本文观察了烧伤患者15天内血浆和RBC的脂质过氧化速率,VE含量和硒谷胱甘肽过氧酶SeGSHPx活性的变化.结果表明血浆脂质过氧化物LPO含量增加,VE含量和SeGSHPx活性降低,以伤后10天为最显著:RBC的自发性溶血百分率和SeGSHPx活性增加,RBC VE含量降低。血浆和RBC的脂质过氧化速率增加和它们的VE含量降低的变化规律相一致。血浆LPO和VE含量以及SeGSHPx活性变化幅度与烧伤严重度相关。
In this paper, the changes of lipid peroxidation rate, VE content and SeGSHPx activity of selenium glutathione peroxidase in plasma and RBC were observed in 15 days.The results showed that plasma lipid peroxides increased LPO content, VE content and SeGSHPx activity Decreased to 10 days after injury the most significant: RBC spontaneous hemolysis percentage and SeGSHPx activity increased, RBC VE content decreased. The increased rate of lipid peroxidation in plasma and RBC is consistent with the change in their VE content. Plasma LPO and VE levels and SeGSHPx activity were related to severity of burn.