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作者报告两例ITP患者,在脾脏摘除后进行脾脏自身移植的试验治疗,获得了可喜结果。这是世界文献中首次报导。两例均为女性,例1:2岁、例2:15岁。均有明显的出血倾向,血小板计数在10万以下,经骨髓穿刺后诊断为ITP。对类固醇、γ-球蛋白、硫唑嘌呤等治疗无效、将摘除的脾脏切成3mm厚、4×4cm的薄片,重量为原脾的1/4,移植于大网膜内。术后观察例1,8个月;例2,7个月均无出血倾
The authors report two patients with ITP who underwent splenectomy and transplant after splenectomy and received promising results. This is the first report in the world literature. Both cases were female, case 1: 2 years old, case 2:15 years old. Have obvious bleeding tendency, platelet count below 100000, diagnosed as ITP after bone marrow puncture. On the steroids, γ-globulin, azathioprine treatment ineffective, the excised spleen cut into 3mm thick, 4 × 4cm of the sheet, the weight of the original spleen 1/4, transplanted in the omentum. Postoperative observation of 1, 8 months; 2,7 months were no bleeding dumping