论文部分内容阅读
由于自身免疫功能低下，各种器官发育不完善，加上各种侵入性操作等因素，早产儿是侵袭性真菌感染的高危群体。早产儿侵袭性念珠菌感染占侵袭性真菌感染的80%以上。侵袭性念珠菌感染以白念珠菌为主，然而近年来近平滑念珠菌、热带念珠菌、光滑念珠菌等非白色念珠菌的感染比率呈逐步上升的趋势。除血培养外，最新的诊断方法如血浆(1-3)-β-D-葡聚糖检测试验、念珠菌聚合酶链反应为诊断侵袭性真菌感染提供了帮助。同时也应关注早产儿预防性抗真菌治疗和经验性抗真菌治疗的问题。“,”Due to low autoimmune function, imperfect development of various organs, coupled with a variety of invasive operations and other factors, premature infants are high-risk groups of invasive fungal infection.Invasive candida infection in premature infants accounts for more than 80% of invasive fungal infection. The main infection rate of invasive candida albicans was candida albicans. However, in recent years, the infection rate of non-candida albicans such as candida albicans, tropical candida, smooth candida and other non-candida albicans showed a gradual upward trend.In addition to blood culture, the latest diagnostic methods such as plasma (1-3)-β-D-glucan test and candida polymerase chain reaction are helpful for the diagnosis of invasive fungal infection. At the same time, attention should also be paid to prophylactic antifungal therapy and empirical antifungal therapy in premature infants.