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本文报告我院1977年1月至1981年6月共收治Graves病359例,伴有浸润性突眼者7例,占1.94％,本文介绍了作者对Graves病浸润突眼的诊治体会。作者提出了诊断浸润性突眼的标淮,即 (1) 有怕光、流泪、眼胀痛、视力模糊等症状,(2) 睡眠时眼脸不能完全闭合,(3) 突眼度大于18mm。本文结合文献讨论了浸润性突眼发病机制,即自身免疫学说和垂体学说。本文报道采用以放疗为主的综合治疗就是以上述两种学说为根据的。垂体加眶后组织区钴~60放疗,放疗面积为4×5cm,在14~25天照射2,130至4,000拉德,平均在21.5天内照射3,072拉德。放疗前一至两周,先给强的松30~40mg/天,症状改善后逐渐
This article reports from January 1977 to June 1981 in our hospital were treated Graves disease 359 cases, with infiltrative exophthalmia in 7 cases, accounting for 1.94%, the author describes the diagnosis and treatment of Graves disease infiltration of exophthalmos. The author proposed the standard for diagnosis of infiltrative exophthalmos, namely: (1) the symptoms of photophobia, tearing, eye pain, blurred vision, etc. (2) the eye face can not be completely closed while sleeping, (3) . This article discusses the pathogenesis of infiltrative exophthalmos, the autoimmune theory and pituitary theory. This article reports that the use of radiotherapy-based comprehensive treatment is based on the above two theories. Pituitary plus orbital tissue area cobalt ~ 60 radiotherapy, radiotherapy area of 4 × 5cm, 14 to 25 days irradiation 2,130 to 4,000 rads, an average of 21.5 days irradiation 3,072 rad. One to two weeks before radiotherapy, giving prednisone 30 ~ 40mg / day, symptoms gradually improved