Ⅰ型肾小管性酸中毒(即远端肾小管性酸中毒)有低钾、酸中毒表现,由于临床表现复杂多变,易被误诊为类风关,原醛、周期性麻痹、格林巴利氏综合征、代谢紊乱及假性骨折等。本文介绍一例以供参考。病历摘要:女性36岁,工人。于1979年4月16月出现乏力活动受限,二日后晨起双下肢瘫痪,二上肢活动无力,不发烧,伴口渴多饮多尿,夜尿多。到本院就诊以周期性麻痹收住神经科病房。既往史,五年前曾患肝炎及慢支常用链霉素及庆大霉素。入院查体T36.5℃、P68次/分、R16次/分、BP106/70mmHg。神清,心肺(一),肝脾未及,双 Type I renal tubular acidosis (ie, distal tubular acidosis) with hypokalemia, acidosis, due to the complex and volatile clinical manifestations, easily misdiagnosed as wind-related, primary aldehyde, periodic paralysis, Green Bayi Syndrome, metabolic disorders and false fractures. This article describes an example for reference. Medical record summary: Female 36 years old, worker. In 1979 April 16th appeared fatigue activity limited, two days later morning paralysis of both lower limbs, two upper limb activity weakness, no fever, with thirsty drink polyuria, nocturia and more. To our hospital to receive periodic paralysis admission neurology ward. Past history, five years ago had hepatitis and chronic bronchitis commonly used streptomycin and gentamicin. Admission examination T36.5 ℃, P68 beats / min, R16 beats / min, BP106 / 70mmHg. God clear, heart and lung (a), liver and spleen yet, double