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大山区钉螺主要分布在稻田中。由于钉螺分布面积大,环境复杂,水源匮乏,灭螺难度大,且费用高昂。为有效控制血吸虫病,设想在进行人畜化疗的同时,以氯硝柳胺糊剂投放于有螺环境的水体中,使其缓慢释放,进行防护性灭螺和灭蚴。本试验的目的,旨在探讨有效杀螺和杀蚴剂量和施用方法,为现场防治工作提供依据。 材料和方法 氯硝柳胺糊剂(以下称糊剂)含氯硝柳胺约50％,为上海第六制药厂配方生产。 1 不同浓度药液杀蚴试验 将糊剂配成2、1、0.5和0.25mg/L四种浓度。吸取各浓度的药液50μl于盖玻片上,每次5张,分别放入30±1条尾蚴,于30min后观察死亡情况。
Large mountain snails are mainly distributed in the rice fields. Due to snail distribution of large area, complex environment, lack of water, snail difficult, and the high cost. In order to control schistosomiasis effectively, it is envisaged that niclosamide paste should be put into the water with snail environment to release slowly and protective snail and kill lacteal while treating human and animal. The purpose of this experiment is to explore the effective kill spiders and kill larvae dose and application methods for the prevention and control of the scene to provide the basis. Materials and methods Niclosamide paste (hereinafter referred to as paste) containing niclosamide about 50%, for the sixth Shanghai Pharmaceutical Factory formula production. 1 different concentrations of liquid kill larvae test will paste dubbed 2,1,0.5 and 0.25mg / L four concentrations. Draw the concentration of the liquid 50μl on the cover glass, each 5, were placed in 30 ± 1 cercariae, observed after 30min death.