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目的评价25%氯硝柳胺乙醇胺盐悬浮剂(SCNE)的实验室和现场杀螺效果。方法在实验室和现场采用SC-NE浸杀、喷洒法灭螺,并与50%氯硝柳胺乙醇胺盐可湿性粉剂(WPN)、25%氯硝柳胺悬浮剂(SCN)进行效果比较。结果室内浸杀:SCNE 24、48 h和72 h LC50值分别为0.058 3、0.044 2 mg/L和0.038 5 mg/L,SCN分别为0.047 4、0.041 2mg/L和0.041 2 mg/L,WPN分别为0.094 7、0.058 3 mg/L和0.044 2 mg/L,清水对照组钉螺死亡率均为0;室内喷洒:SC-NE剂量为2、4、8 g/m2,用药3 d后钉螺死亡率均为100%,相应剂量组SCNE杀螺效果均高于WPN,与SCN相一致。现场浸杀:除1 g/m3浸杀钉螺1 d钉螺死亡率为93.33%外,SCNE 2、4、8 g/m3浸杀钉螺1、2、3 d钉螺死亡率均为100%;现场喷洒:SCNE剂量>2 g/m2,用药3 d后钉螺死亡率均>89%,相应剂量组SCNE杀螺效果均高于WPN。结论SCNE具有较好的实验室和现场杀螺效果,为新型高效、使用方便的灭螺药物剂型。
Objective To evaluate the laboratory and field effectiveness of 25% niclosamide ethanolamine salt suspension (SCNE) in laboratory. Methods SC-NE immersion and spraying were used to kill snails in laboratory and field. The effects were compared with 50% niclosamide ethanolamine wettable powder (WPN) and 25% niclosamide suspension (SCN). Results Indoor immersion: The LC50 values of SCNE at 24 h, 48 h and 72 h were 0.058 3, 0.044 2 mg / L and 0.038 5 mg / L, SCN were 0.047 4, 0.041 2 mg / L and 0.041 2 mg / L, Were 0.094 7, 0.058 3 mg / L and 0.044 2 mg / L, respectively. The mortality of snail in the fresh water control group was 0; indoor spray: the dosage of SC-NE was 2, 4 and 8 g / The rates were 100%, the corresponding dose group SCNE kill spiral effect were higher than the WPN, consistent with the SCN. On-the-spot immersion: except for 1 g / m3 submerged snail 1 d snail mortality was 93.33% SCNE 2, 4, 8 g / m3 submerged snails 1, 2 and 3 d death rates were 100% Oncomelania; spraying : The SCNE dose> 2 g / m2, the mortality of Oncomelania snails was> 89% after 3 days of treatment, and the SCNE kill effect of the corresponding dose group was higher than that of WPN. Conclusion SCNE has good laboratory and on-site snail killing effect, and is a new type of highly effective and easy-to-use snail medication.