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目的总结肾嗜酸细胞腺瘤的CT表现及病理基础,提高肾嗜酸细胞腺瘤的诊疗水平。方法回顾性分析12例肾嗜酸细胞腺瘤患者的临床、影像和病理学资料。结果男7例,女5例,年龄40~65岁。均单侧单发,边界清晰。9例位于右肾。5例呈均匀等或略低密度,明显强化,7例中央可见瘢痕区。术前均诊断为肾癌,行肾切除术。肉眼观察肿瘤边界清楚,质地均匀。光镜下瘤细胞排列成腺泡管状或实性片状,无明显异型性和核分裂相。电镜下胞浆内见大量线粒体。结论肾嗜酸细胞腺瘤作为一种少见的肾脏良性腺瘤,其影像特征有助于术前诊断及指导治疗。
Objective To summarize the CT manifestations and pathological basis of renal oncocytoma and to improve the diagnosis and treatment of renal oncocytoma. Methods The clinical, imaging and pathological data of 12 patients with renal oncocytoma were retrospectively analyzed. Results 7 males and 5 females, aged 40 to 65 years old. Single unilateral, clear boundary. 9 cases located in the right kidney. 5 cases were uniform or slightly lower density, significantly enhanced, 7 cases of central visible scar area. Preoperative diagnosis of renal cell carcinoma, nephrectomy. Visual observation of tumor boundary clear, uniform texture. Light microscopy of tumor cells arranged in acinar tubular or solid sheet, no significant atypia and mitotic phase. A large number of mitochondria were seen in cytoplasm under electron microscope. Conclusion Renal acidophilic adenoma as a rare renal benign adenoma, its imaging features help to preoperative diagnosis and treatment.