破伤风和白喉引起严重影响健康的问题遍及全世界。自从在人群及其周围环境中,发现白喉棒状杆菌和破伤风梭状杆菌广泛地存在以来,未免疫人群面临着感染这两种疾病的危险。世界卫生组织估计每年由于破伤风可其并发症引起50多万人的死亡。美国1966～1976年十年间,疾病控制中心的发病 Tetanus and diphtheria cause serious health problems throughout the world. Since the widespread presence of Corynebacterium diphtheriae and Clostridium tetani in both the human population and their surroundings, uninjured populations are at risk of contracting both diseases. WHO estimates the deaths of more than 500,000 people each year due to its complications due to tetanus. The United States from 1966 to 1976 ten years, the incidence of disease control center