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目的探讨血清微量元素和生殖激素水平的测定在男性不育症诊断中的临床价值。方法应用原子吸收分光光度法和放免法对17例男性不育者和21例正常男子分别测定血清微量元素和生殖激素水平。结果不育组血清锌明显减低，而黄体生成素（LH）和泌乳素（PRL）则高于对照组（P＜0．05）；对照组锰含量与卵泡刺激素（FSH）、LH、PRL均呈负相关，而锌和铁与孕酮（P）正相关（P＜0．05），不育组锌与FSH、LH皆呈显著负相关（P＜0．01），铁与P亦呈负相关（P＜0．05）。结论同时检测血清锌、锰及FSH、LH、PRL水平可为男性不育症病因诊断及治疗提供有参考价值的实验依据。
Objective To investigate the clinical value of serum trace elements and reproductive hormones in the diagnosis of male infertility. Methods Serum trace elements and reproductive hormones were measured by atomic absorption spectrophotometry and radioimmunoassay in 17 male infertility and 21 normal men. Results Serum zinc was significantly decreased in the infertility group, while the levels of luteinizing hormone (LH) and prolactin (PRL) in the control group were significantly higher than those in the control group (P <0.05) (P <0.05). There was a significant negative correlation between zinc and FSH, LH in sterility group (P <0.01), iron and P Was negatively correlated (P <0.05). Conclusion Simultaneous detection of serum zinc, manganese and FSH, LH and PRL levels may provide experimental evidence for the diagnosis and treatment of male infertility.