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与15年前相比,二乙撑三胺五乙酸~(99m)锝(~(99m)Tc-DTPA)用于肾、脑闪烁造影已较多见。由于~(99m)Tc-DTPA 只通过肾小球滤过从血浆中排出,因此,注射~(99m)Tc-DTPA 后,通过它的血浆清除率测定就可获得肾小球滤过率(GFR)。运用~(99m)Tc-DTPAγ照相可获得相当出色的肾造影影片,可得到肾和尿路的影像,并可得到单个肾脏的总 GFR(相对肾功能)。对于成年人,无需采集血和尿标本,从肾造影就可准确地计算出 GFR(绝对肾功能)。然而,外部测量受几何形状的影响,因此,成人的这种方法未经校正而用于儿童是无效的。
Compared with 15 years ago, diethylenetriaminepentaacetic acid ~ (99m) Tc (~ (99m) Tc-DTPA) is more commonly used in renal and brain scintigraphy. Because ~ (99m) Tc-DTPA is only excreted from the plasma by glomerular filtration, glomerular filtration rate (GFR) is measured by its plasma clearance after ~99m Tc-DTPA injection ). The use of ~ (99m) Tc-DTPAgamma imaging produces excellent imaging of the nephrolithiasis, images of the kidney and urinary tract, and total GFR (relative renal function) of a single kidney. For adults, GFR (absolute renal function) can be accurately calculated from renal angiography without the need to collect blood and urine samples. However, the external measurement is affected by the geometry, therefore, this method for adults is not effective for children without correction.