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目的探讨经皮经肝胆道引流术对肝癌合并阻塞性黄疸患者的临床治疗效果。方法回顾性分析孟州市中医院自2013年1月至2015年1月收治原发性肝癌合并阻塞性黄疸患者60例,诊断明确后因多种原因仅采用PTBD术减黄治疗,未对肿瘤本身进行治疗,对患者手术前后肝功能情况进行对比分析,并计算患者生存时间。结果本组病例手术均获得成功,以术后胆红素水平较术前下降30%为治疗有效,有效率达80%;术后患者总胆红素、直接胆红素值、血清谷丙及谷草转氨酶均较引流前明显下降,但血清白蛋白指标比较差异没有统计学意义;术后1个月生存率为96.7%,2个月生存率为63.3%,3个月生存率为41.7%,4个月生存率为41.7%,5个月生存率为21.7%,6个月生存率为11.7%,7个月生存率为1.7%,中位数为2.5个月。结论肝癌合并阻塞性黄疸患者积极行经皮经肝胆道引流术有利于改善患者肝功能,延长患者生存期。
Objective To investigate the clinical effect of percutaneous transhepatic biliary drainage on patients with liver cancer complicated with obstructive jaundice. Methods Retrospective analysis of Mengzhou City Hospital from January 2013 to January 2015 admitted to primary liver cancer patients with obstructive jaundice in 60 cases, after a clear diagnosis of a variety of reasons only PTBD treatment of yellow, no tumor Itself for treatment of patients with liver function before and after surgery comparative analysis and calculation of patient survival time. Results The operation of this group of patients were successful. The postoperative bilirubin level was reduced by 30% compared with that before operation, and the effective rate was 80%. The total bilirubin, direct bilirubin, serum alanine, Aspartate aminotransferase was significantly lower than before drainage, but the serum albumin index was no significant difference; 1 month survival rate was 96.7%, 2 months survival rate was 63.3%, 3 months survival rate was 41.7% The 4-month survival rate was 41.7%, the 5-month survival rate was 21.7%, the 6-month survival rate was 11.7%, the 7-month survival rate was 1.7%, and the median was 2.5 months. Conclusion The positive percutaneous transhepatic biliary drainage in patients with liver cancer complicated with obstructive jaundice is helpful to improve the liver function and prolong the survival of patients.