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根据现代的概念,嗜碱细胞和肥大细胞是速发型,也可能是迟发型超敏反应的靶细胞。 Shelly氏指出,嗜硷细胞脱颗粒间接试验,可作为速发型超敏反应的诊断。但必须指出,在完整的嗜硷细胞被动性脱颗粒反应中,测定循环抗体的间接反应技术复杂。作者使用直接法测定某些过敏原对风湿病患者嗜硷细胞特异性地损伤的嗜硷细胞。在有特异性抗原存在时,测定嗜硷细胞脱颗粒反应以不添加过敏原的损伤细胞数作为对照。把弛缓性和目前潜在复发的风湿病患者作比较,这些病人作嗜硷细胞脱颗粒检查时,向末稍血中添加肝组
Basis of modern concepts, basophils and mast cells are fast-haired and may also be target cells for delayed-type hypersensitivity. Shelly pointed out that alkalophil degranulation indirect test can be used as a diagnosis of immediate hypersensitivity reaction. However, it must be pointed out that in the intact basophilic passive degranulation reaction, the indirect reaction assay of circulating antibodies is complex. The authors used the direct method to determine the presence of alkaloids in allergic cells that are specifically damaged by alkaloids in rheumatic patients. In the presence of specific antigens, the alkaloid degranulation was measured as the number of injured cells without allergen addition. The flaccidity and the current potential recurrence of rheumatoid patients for comparison, these patients for basophil degranulation examination, the terminal blood to the liver group