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本研究采用抗PKP、PSK及KNK－1单克隆抗体对68例前列腺癌患者的石蜡组织切片进行免疫组织化学（ABC）染色，观察免疫染色反应后阳性癌细胞的比率和染色强度及其与肿瘤分化度之间的关系。结果表明：抗PAP、PSA及HNK－1单克隆抗体免疫组化反应的阳性率分别为57．3％、72％及引％，对三种单克隆免疫组化反应的总阳性率为97．1％。抗PAP免疫组化反应与肿瘤分化度无关；而抗PSA及HNK－1免疫组化反应与肿瘤分化呈正相关。
In this study, paraffin sections from 68 patients with prostate cancer were immunohistochemically stained with anti-PKP, PSK and KNK-1 monoclonal antibodies to observe the ratio and staining intensity of positive cancer cells after immunostaining reaction and their correlation with tumor The relationship between the degree of differentiation. The results showed that the positive rates of anti-PAP, PSA and HNK-1 monoclonal antibodies were 57.3%, 72% and 97%, respectively. The positive rates of anti-PAP, PSA and HNK-1 monoclonal antibodies were 97% 1%. The anti-PAP immunohistochemical reaction has nothing to do with the degree of tumor differentiation; while the anti-PSA and HNK-1 immunohistochemical reaction and tumor differentiation was positively correlated.