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目的探讨甲状腺１ｈ摄锝参数诊断甲状腺机能亢进症（甲亢）的临床价值。方法对６９例各型甲亢患者和１３０例正常人，按常规方法测定３ｈ、２４ｈ吸碘率后，口服９９ｍＴｃＯ４法进行甲状腺１ｈ静态显像，用感兴趣区（ＲＯＩ）技术计算甲状腺区的总计数、象素数，摄锝参数＝甲状腺部位总计数（甲状腺象素数×采集时间）。摄锝参数＞１０提示甲状腺摄取功能增强，计算摄锝参数在各型甲亢的均数及诊断灵敏度。用相关分析由１ｈ摄锝参数推算２４ｈ吸碘率。结果各型甲亢摄锝参数显著高于正常（Ｐ＜０．００１），诊断甲亢总的灵敏度为８６．９％（６０／６９）。摄锝参数（Ｘ）与２４ｈ吸碘率（Ｙ）呈显著正相关（ｒ＝＋０．７８４，Ｐ＜０．００１），回归方程为Ｙ＝０.８Ｘ十５２．４。用该方程验算结果与实测值误差＜１０％。结论甲状腺１ｈ摄锝参数与２４ｈ吸碘率密切相关，可准确反映甲状腺摄取功能，受干扰少，对诊断甲亢有重要价值。
Objective To investigate the clinical value of thyroid 1h imaging of technetium in the diagnosis of hyperthyroidism (hyperthyroidism). Methods Ninety-nine patients with hyperthyroidism and 130 normal controls were enrolled in this study. After 3 hours and 24 hours of iodine uptake, the 99mTcO4 method was used to perform static imaging of thyroid for 1 hour. The total number of thyroid gland regions was calculated by ROI technique , Number of pixels, photo-technetium parameter = thyroid site total count (thyroid pixel number x acquisition time). Photographic Tc parameters> 10 suggest that the thyroid uptake function, calculate the number of episodes of technetium in all types of hyperthyroidism and diagnostic sensitivity. Correlation analysis by 1h shooting technetium parameters estimated 24h iodine absorption rate. Results The Tc of hyperthyroidism was significantly higher than that of normal (P <0.001). The overall sensitivity of diagnosis of hyperthyroidism was 86.9% (60/69). There was a significant positive correlation between uptake of technetium (X) and iodine uptake rate (Y) of 24h (r = +0.784, P <0.001). The regression equation was Y = 0.8X + 52.4. The results of the equation with the measured error of <10%. Conclusions Thyroid 1h phototaxis is closely related to iodine uptake rate in 24h, which can accurately reflect the function of thyroid uptake and less interference. It is of great value in the diagnosis of hyperthyroidism.