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目的评价A型肉毒毒素(BTXA)治疗小样本的急性共同性内斜视的效果。设计回顾性病例系列。研究对象6例6~34岁急性共同性内斜视患者。方法所有患者在肌电放大仪引导下行双侧内直肌注射BTXA一次,两眼分别为2.5单位,注射前后行三棱镜交替遮盖检查斜视度,同视机及立体视觉检查图检查。主要指标斜视度及立体视功能。结果 6例患者随访时间4~39个月。注射前平均内斜视度数为(43.3±1.0)△,最后一次随访时为(3.3±8.2)△,其中5例眼位正位。注射前1例患者具有远立体视,2例患者近立体视为600秒和40秒,注射后5例患者具有远、近立体视(3例40秒,1例60秒,1例200秒)。结论本文有限的资料表明,BTXA是治疗急性共同性内斜视有效的可选择方法 。
Objective To evaluate the efficacy of botulinum toxin type A (BTXA) in the treatment of acute common esotropia in small samples. Design retrospective case series. Participants Six patients aged 6 to 34 years with acute esotropia. Methods All patients underwent bilateral intramuscular injections of BTXA once under the guidance of EMG. The two eyes were 2.5 units respectively. Prism was alternately covered before and after injection to check the degree of strabismus, and the same examination was performed with the stereoscopic vision examination. Main indicators of strabismus and stereopsis function. Results Six patients were followed up for 4 to 39 months. The average number of esotropia before injection was (43.3 ± 1.0) △, the last follow-up was (3.3 ± 8.2) △, of which 5 patients were orthophorized. One patient had tele-stereopsis before injection, two patients had near stereo vision of 600 seconds and 40 seconds, and five patients had far and near stereopsis (3 for 40 seconds, 1 for 60 seconds and 1 for 200 seconds) . Conclusions The limited data presented in this paper suggest that BTXA is an effective alternative to the treatment of acute common esotropia.