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小儿气管插管使用琥珀胆碱可引起严重的副作用,包括心动过缓、心律失常、术后肌痛、咬肌痉挛和恶性高热。拟行斜视矫正术的小儿使用琥珀胆碱更增加后两者的危险性。阿屈可林(atracurium)作为一种非去极化肌松药,不引起象琥珀胆碱那样的副作用,更重要的是不引起咬肌痉挛和恶性高热。本研究的目的是测定氟烷麻醉下择期斜视矫正术小儿使用两种小剂量阿屈可林(0.25mg/kg 和0.3mg/kg,分别约为ED_(95)例1倍和1.5倍)的插管条件和恢复时间,并与常用剂量0.4mg/kg(约为ED_(95)的2倍)的结果作对比。
The use of succinylcholine in pediatric endotracheal tubes can cause serious side effects, including bradycardia, arrhythmia, postoperative muscle ache, masseter muscle spasms, and hyperpyrexia. The proposed strabismus correction of pediatric use of succinylcholine increased risk of both. As a non-depolarizing muscle relaxant, atracurium does not cause side effects like succinylcholine, and more importantly, does not cause masseter muscle spasms and hyperpyrexia. The aim of this study was to determine the effect of halothane anesthesia on elective strabismus surgery in children with two low doses of acyclidine (0.25 and 0.3 mg / kg, approximately 1 and 1.5 times ED 95) Intubation conditions and recovery time, and with the usual dose of 0.4mg / kg (about ED_ (95) 2 times the results for comparison).