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胡黄连制剂picroliv是从植物胡黄连(Pi-erorhiza kurrooa)根中提取的环烯醚萜甙类的稳定混晶,主要含有胡黄连苦甙Ⅰ(picro-side Ⅰ)和胡黄连甙(kutkoside),是治疗各种肝毒的有效药物。据报道,picroliv的膜稳定作用及抗氧化作用与其肝保护功能有关。脂质代谢障碍在肝损伤中起重要作用。本文研究了picroliv对三硝基甲苯和胆固醇诱发的大鼠高血脂的脂质蛋白代谢作用。
Picroliv is a stable mixed crystal of iridoids extracted from the roots of Pi-erorhiza kurrooa and contains mainly picro-side I and kutkoside. , is an effective drug for the treatment of various liver poisoning. According to reports, the film stabilization and antioxidation of picroliv are related to its liver protection function. Lipid metabolism disorders play an important role in liver damage. This study investigated the lipid metabolism of hyperlipidemia in rats induced by picroliv against trinitrotoluene and cholesterol.