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目的 :探讨多学科综合治疗对手术切除不完全的Ⅲ期非小细胞肺癌的生存影响。方法 :分析 4 6例手术切除不完全的Ⅲ期非小细胞肺癌患者 (ⅢA32例 ,ⅢB14例 )的远期疗效 ,比较术后化疗和术后化放疗对生存期的影响。结果 :全组的中位生存期 ,1年、2年和 3年生存率分别为 15个月 ,6 9 6 % ,2 6 1%和 13 1% ;术后化疗组分别为 15个月 ,6 5 2 % ,18 2 %和9 1% ;而术后化放疗组则分别为 18 5个月 ,73 9% ,34 8%和 17 4 %。两组的生存率无显著差别 (P >0 0 5 )。结论 :手术切除不完全的Ⅲ期非小细胞肺癌经多学科综合治疗后生存率提高 ;与术后化疗相比 ,术后化放疗并不能显著延长生存率
Objective: To investigate the multidisciplinary comprehensive treatment of surgically resected incomplete stage Ⅲ non-small cell lung cancer survival impact. Methods: The long-term efficacy of 46 patients with stage Ⅲ non-small cell lung cancer (ⅢA32, ⅢB14) with incomplete resection was analyzed. The effects of postoperative chemotherapy and postoperative radiotherapy on survival were compared. Results: The median survival, 1-, 2- and 3-year survival rates were 15 months, 69.6%, 26.1% and 13.1% respectively in the whole group; 15 months in the postoperative chemotherapy group, 6 5 2%, 18 2% and 9 1%, respectively. The postoperative radiotherapy group was 18 5 months, 73 9%, 34 8% and 17 4% respectively. There was no significant difference in survival between the two groups (P> 0.05). Conclusions: Survival rate of incompletely resected stage Ⅲ non-small cell lung cancer after multidisciplinary treatment is improved. Compared with postoperative chemotherapy, postoperative radiotherapy does not significantly prolong the survival rate