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[目的]评价放射加热疗治疗局部晚期非小细胞肺癌(NSCLC)的疗效。(方法)采用随机配对的方法将不能手术的ⅢaⅢb。期NSCLC患者分为两组,A组采用放疗加热疗,B组单纯放疗。(结果〕A组和B组肿瘤有效率(C+PR)分别为91.18%、82.35%(P=0.05);A组急性放射反应和后期放射损伤较B组明显减轻(P值分别为0.03和0.035);3年生存率分别为11.76%和8.82%(P=00158),3年局控率为7.84%和5.88%(P=0.0398),3年无远处转移率分别为19.16%和18.42%(P=0.0213)。(结论)放疗加热疗治疗局部晚期NSCDLC疗效优于单纯放射治疗,且可减轻急性放射反应和后期放射损伤。
[Objective] To evaluate the efficacy of radiotherapy in the treatment of locally advanced non-small cell lung cancer (NSCLC). (Method) Inoperable IIIaIIIb will be performed using a random pairing method. Patients with stage NSCLC were divided into two groups. Group A was treated with radiotherapy and group B was treated with radiotherapy alone. (Results) The tumor effective rates (C+PR) in group A and B were 91.18% and 82.35%, respectively (P=0.05). The acute radiation reaction and late radiation injury in group A were significantly lower than those in group B (P values were 0. 03 and 0.035); 3-year survival rates were 11.76% and 8.82% (P=00158), respectively, and 3-year control rates were 7.84% and 5.88% (P=0.0398). There was no distance in 3 years. The metastasis rates were 19.16% and 18.42%, respectively (P=0.0213).(Conclusion) The radiotherapy hyperthermia therapy is superior to radiotherapy alone in the treatment of locally advanced NSCDLC, and can reduce acute radiation reaction and radiation damage in the later period.