血型糖蛋白(Glycophorins,GPH)是人红细胞膜上的一族糖蛋白,其分子含有MNSs血型系统抗原~([1])。近十年来,人红细胞膜CPH的结构多态性(polymorphism)及其与恶性疟原虫(plasmodium Falciparum)侵犯人红细胞的关系,已引起广泛注意~([1,2])每个待检者血中含有多种GPH分子~([1]),而在一定的群体中存有各种类型的GPH结构变种~([3-7]),后者即反映了其结构的多态性。 Glycophorins (GPH) are a group of glycoproteins on the membrane of human erythrocytes, and their molecules contain MNSs blood group antigen [1]. Over the past decade, the structural polymorphism of human erythrocyte membrane CPH and its association with human erythrocytes affecting plasmodium falciparum have attracted widespread attention ([1,2]). Each candidate blood Contains a variety of GPH molecules ~ ([1]), and in some groups there are various types of GPH structure ~ ([3-7]), the latter reflects its structural polymorphism.