通过光镜观察染色的有丝分裂染色体,可以看到人类Y染色体的许多结构异常。从那些性表型与异常核型的相关性已推断出睾丸的决定因子位于人类Y染色体。然而由于染色体带研究的精确性是有局限性的,异常Y染色体结构的研究也经常出现不一致的结果。因此,关于睾丸的决定因子应定位在Y染色体的短臂上还是着丝粒部位,或定位在长臂上仍在继续争论之中。克隆Y染色体DNA顺序成为Y染色体分析的一种新工具。现已能鉴定出Y染色体DNA顺序的一些类型。Y染色体的特异重复 By light microscopy of stained mitotic chromosomes, one can see many of the structural abnormalities in the human Y chromosome. From the correlation between the phenotypes and the abnormal karyotypes it has been deduced that the determinants of the testis are located on the human Y chromosome. However, due to the limitations of the accuracy of chromosome band studies, the study of aberrant Y chromosome structure often shows inconsistent results. Therefore, it remains to be argued that the determinant of the testicle should be located on the short arm or centromere of the Y chromosome or on the long arm. Cloning of the Y-chromosome DNA sequence becomes a new tool for Y-chromosome analysis. It is now possible to identify some types of Y-chromosome DNA sequences. Y chromosome specific repeat