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目的:观察驱寒活络止痛方联合西药治疗风湿性关节炎的临床疗效。方法:选取107例风湿性关节炎患者进行研究,按随机数字表法分为观察组54例与对照组53例。对照组口服美洛昔康片,观察组在对照组治疗基础上联合驱寒活络止痛方,对比2组治疗前后血液流变学指标、临床疗效、安全性的差异性。结果:观察组总有效率为92.6%,高于对照组的总有效率(75.5%),2组比较,差异有统计学意义(P<0.05)。治疗前,2组血浆黏度、纤维蛋白原、全血高切黏度值比较,差异均无统计学意义(P>0.05);治疗后,2组各项指标均较治疗前改善,差异均有统计学意义(P<0.05),观察组各项指标值均高于对照组,差异均有统计学意义(P<0.05)。结论:驱寒活络止痛方联合西药治疗风湿性关节炎可有效改善患者的血液流变学指标,缓解临床症状,疗效佳且安全性较好。
Objective: To observe the clinical effect of “Qionghan Huolimu Recipe” combined with western medicine in the treatment of rheumatoid arthritis. Methods: A total of 107 patients with rheumatoid arthritis were selected and divided into observation group (n = 54) and control group (n = 53) by random number table. The control group was treated with meloxican tablets orally, and the observation group was treated with the combination of expelling cold and invigorating pain and relieving pain in the control group. The differences of hemorheology, clinical efficacy and safety between the two groups before and after treatment were compared. Results: The total effective rate in the observation group was 92.6%, higher than that in the control group (75.5%). There was significant difference between the two groups (P <0.05). Before treatment, there was no significant difference in the viscosity of plasma, fibrinogen and whole blood between the two groups (P> 0.05). After treatment, the indexes in both groups improved compared with before treatment, with statistical differences (P <0.05). The indexes in the observation group were all higher than those in the control group (P <0.05). Conclusion: The treatment of rheumatoid arthritis by expelling cold and expelling pain-relieving prescription in combination with western medicine can effectively improve the hemorrheological indexes of patients and relieve the clinical symptoms, with good curative effect and good safety.