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目的：探讨血清乳酸脱氢酶（LDH）和α-羟丁酸脱氢酶（HBDH）的变化与急性白血病患者疗效关系。方法：观察45名急性白血病人血清LDH和HBDH变化。结果：急性白血病人血清LDH和HBDH显著升高，病情缓解后可降低。LDH和HBDH值与外周血幼稚细胞数呈正相关。结论：血清LDH和HBDH是判定急性白血病疗效的有效指标。
Objective: To investigate the relationship between the changes of serum lactate dehydrogenase (LDH) and α-hydroxybutyrate dehydrogenase (HBDH) and the efficacy of acute leukemia patients. Methods: The changes of serum LDH and HBDH in 45 acute leukemia patients were observed. Results: The serum LDH and HBDH in patients with acute leukemia were significantly elevated and decreased after remission. LDH and HBDH values were positively correlated with the number of immature cells in peripheral blood. Conclusion: Serum LDH and HBDH are effective indexes for judging the curative effect of acute leukemia.