Fogang granitic batholith, the largest Late Mesozoic batholith in the Nanling region, has an exposure area of ca. 6000 km2. Wushi diorite-hornblende gabbro body is situated at the northeast part of the ba- tholith. Both the granitic batholith main body and the diorite-hornblende gabbro body belong to high-K calc alkaline series. Compared with the granitic main body, the Wushi body has lower Si (49%―55%), higher Fe, Mg, Ca, lower REE, less depletion of Eu, Ba, P, Ti, and obvious depletion of Zr, Hf. Zircon LA-ICP-MS dating and the mineral-whole rock isochron dating reveal that Fogang granitic main body and Wushi body were generated simultaneously at ca. 160 Ma. The Fogang granitic main body has high (87Sr/86Sr)i ratios (0.70871―0.71570) and low εNd(t) values (?5.11―?8.93), suggesting the origins of the granitic rocks from crustal materials. Their Nd two-stage model ages range from 1.37―1.68 Ga. The Sr and Nd isotopic compositions and the Nd model ages of the granitic rocks may suggest that the giant Fogang granitic main body was generated from a heterogeneous source, with participation of mantle component. Wushi diorite-hornblende gabbro is an unusual intermediate-basic magmatic rock series, with high (87Sr/86Sr)i ratios (0.71256―0.71318) and low εNd(t) values (?7.32―?7.92), which was possibly formed through mixing between the mantle-derived juvenile basaltic magma and the magma produced by the dehydration melting of lower crustal basaltic rocks. Fogang granitic batholith, the largest Late Mesozoic batholith in the Nanling region, has an exposure area of ​​ca. 6000 km2. Wushi diorite-hornblende gabbro body is situated at the northeast part of the ba- tholith. Both the granitic batholith main body and the Compared to the granitic main body, the Wushi body has lower Si (49% -55%), higher Fe, Mg, Ca, lower REE, less depletion of Eu, Ba, P, Ti, and obvious depletion of Zr, Hf. Zircon LA-ICP-MS dating and the mineral-whole rock isochron dating reveal that Fogang granitic main body and Wushi body were simultaneously produced at ca. 160 Ma. The Fogang granitic The bodies of the high (87Sr / 86Sr) i ratios (0.70871-0.71570) and low εNd (t) values ​​(? 5.11-? 8.93), suggesting the origins of the granitic rocks from crustal materials. Their Nd two-stage model ages range from 1.37-1.68 Ga. The Sr and Nd isotopic compositions and the Nd model ages of the granitic rocks may suggest that the giant Fogang granitic main body was generated from a heterogeneous source, with participation of mantle component. Wushi diorite-hornblende gabbro is an unusual intermediate-basic magmatic rock series, with high (87Sr / 86Sr) i ratios (0.71256-0.71318) and low εNd (t) values ​​(? 7.32-? 7.92) which was formed by mixing between the mantle-derived juvenile basaltic magma and the magma produced by the dehydration melting of lower crustal basaltic rocks.