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目的 研讨早产儿革兰阴性菌败血症肝功能变化。方法 将 2 0 0 0年 3月～ 2 0 0 4年 5月在厄立特里亚首都儿童医院新生儿病房收治的早产儿革兰阴性杆菌败血症 2 7例和早产儿凝固酶阴性葡萄球菌败血症 1 5例肝功能进行比较。结果 早产儿革兰阴性杆菌败血症肝功能异常 1 3例 (48.2 % ) ,早产儿凝固酶阴性葡萄球菌败血症的肝功能异常 2例 (1 3 .3 % ) ,两者碱性磷酸酶无区别 ;革兰阴性菌中肺炎克雷伯杆菌败血症有肝功能异常 6例 (66 .7% ) ,铜绿假单胞菌败血症无肝功能异常。结论 早产儿革兰阴性细菌性败血症尤其是革兰阴性菌败血症可有肝功能异常。
Objective To investigate the changes of liver function in pre-term Gram-negative bacteria sepsis. Methods From March 2000 to February 2004, 27 cases of gram-negative bacteremia and 17 cases of coagulase-negative staphylococcal septicemia in premature infants admitted to neonatal wards of Capital Children’s Hospital of Eritrea were enrolled. Function to compare. Results There were 13 cases (48.2%) of liver dysfunction in pre-term Gram-negative bacilli sepsis and 2 cases (13.3%) of liver dysfunction in coagulase-negative staphylococcal sepsis in preterm infants. There was no difference between the two groups in alkaline phosphatase; Gram-negative bacteria Klebsiella pneumoniae septicemia have liver abnormalities in 6 cases (66.7%), Pseudomonas aeruginosa sepsis without liver dysfunction. Conclusion Gram-negative bacterial sepsis in preterm children, especially Gram-negative sepsis, may have liver dysfunction.